Primary Bone Cancer: Stages

What does stage of cancer mean?

The stage of a cancer is how much and how far the cancer has spread in your body. Your healthcare provider uses exams and tests to find out the size of the cancer and where it is. He or she can also see if the cancer has grown into nearby areas, and if it has spread to other parts of your body. The stage of a cancer is one of the most important things to know when deciding how to treat the cancer.

What are the stages of primary bone cancer?

For primary bone cancer (cancer that starts in the bones), the stage is determined by 2 things: where the cancer is in the body and the grade of the cancer.

The grade of the cancer describes how quickly the cancer is likely to grow and spread, based on how cancer cells from the biopsy look under the microscope. Primary bone cancer has 4 grades. Low-grade (grade 1 or 2) cancers look more like normal bone cells. These cancers are usually slow-growing and less likely to grow and spread. High-grade (grade 3 or 4) cancers look very abnormal. They are more likely to grow quickly and spread.

The stage of a bone cancer is based on the grade, the size of the main tumor, and if it has spread outside the bone. Most bone cancers are grouped into one of 4 stages. The stages are named using the Roman numerals I to IV:

  • Stage I. The cancer is confined to the bone and is low-grade.

  • Stage II. The cancer is confined to the bone but is high-grade.

  • Stage III. The cancer is in more than one place in the same bone and is high-grade.

  • Stage IV. The cancer has spread outside the bone. It can be low- or high-grade.

Stage I and II cancers can be further divided (into A and B) based on the size of the tumor. Stage IV cancers can be further divided (into A and B) based on where the cancer has spread.

Talking with your healthcare provider

Once your cancer is staged, your healthcare provider will talk with you about what the stage means for your treatment. Make sure to ask any questions or talk about your concerns.

Online Medical Reviewer: Alteri, Rick, MD
Online Medical Reviewer: Levin, Mark, MD
Last Review Date: 2/21/2016
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