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NAFLD is a common disease of the liver. It occurs when there is too much fat in the liver. If NAFLD is severe, it can cause liver damage that appears similar to the damage caused by drinking too much alcohol. However, NAFLD is not caused by drinking alcohol. This sheet tells you more about NAFLD and how it can be managed.
The liver is an organ located in the upper right side of the abdomen. It has many important functions. These include:
Metabolizing proteins, carbohydrates, and fats
Making a substance called bile that helps break down fats
Storing and releasing sugar (glucose) into the blood to give the body energy
Removing toxins from the blood
Helping with the clotting of blood
A healthy liver may contain some fat. But if too much fat builds up in the liver, this causes NAFLD. NAFLD can be mild, causing fatty liver. Or it can be more severe and show inflammation, as well as the fat, and cause non-alcoholic steatohepatitis (NASH). NASH can lead to cirrhosis. With fatty liver, the liver simply contains more fat than normal. This extra fat usually causes no damage to the liver. With NASH, the fatty liver becomes inflamed over time. NASH is serious because it can lead to scarring of the liver (fibrosis). Over time, the scarring may lead to cirrhosis, which can eventually cause liver failure or liver cancer.
The cause of NAFLD is unknown. But certain risk factors make the problem more likely to occur. These include:
Prediabetes or diabetes
High levels of cholesterol and triglycerides (types of fat found in the blood)
Exposure to certain medications
Most people with NAFLD have no symptoms. If symptoms do occur, they can include:
Loss of appetite
Nausea and vomiting
Abdominal pain and cramping
Yellowing of the skin and eyes (jaundice); dark urine, or light-colored stools
Swelling in the abdomen or legs
Your health care provider may suspect you have NAFLD if routine blood tests show elevated levels of liver enzymes. This may mean that a liver problem is possible. One or more imaging tests, such as an ultrasound, CT scan, or MRI scan, may be done. Additional blood tests may be done to look for other causes of liver disease. A liver biopsy may also be done. During this test, a hollow needle is used to remove a tiny amount of tissue from the liver. This tissue is then studied in a lab. This test can detect signs of damage involving liver tissue. It can also help determine the cause of the damage and tell the difference between fatty liver and NASH.
Treatment for NAFLD varies for each person. Your doctor will monitor your health and treat any symptoms or underlying health problems you have. Your doctor will also work with you to control your risk factors so that damage to your liver is less likely. Your plan may include:
Losing excess weight
Getting regular exercise
Controlling diabetes and high cholesterol or triglyceride levels
Taking medications and vitamins as prescribed by your doctor
Avoiding drinking alcohol
Eating a healthy and balanced diet
If NAFLD is caught early, it can be managed with treatment. Your health care provider will discuss further treatment options with you as needed.
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