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SORAFENIB (soe RAF e nib) is a chemotherapy drug. It is used to treat liver cancer and kidney cancer.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after meals. Do not take with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fever or chills, sore throat
high blood pressure
pain, tingling, numbness in the hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
swelling in a leg
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
loss of appetite
medicines for seizures like oxcarbazepine, phenobarbital, phenytoin
medicines that treat blood clots like amediplase, streptokinase
medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
some medicines for sleep like secobarbital
St. John's Wort
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
infection (especially a virus infection such as chickenpox, cold sores, or herpes)
an unusual or allergic reaction to sorafenib, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor for regular check ups. You will need to have blood work while you are taking this medicine.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
Men and women should use effective birth control while taking this medicine and for 2 weeks after stopping this medicine. Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
If you are going to have surgery or any other procedures, tell your doctor you are taking this medicine.
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