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ACETAMINOPHEN; CHLORPHENIRAMINE; DEXTROMETHORPHAN; PHENYLEPHRINE (a set a MEE noe fen; klor fen IR a meen; dex troe meth OR fan; fen il EF rin) is a combination of a pain reliever, an antihistamine, a cough suppressant, and a decongestant. It is used to treat the aches and pains, cough, fever, congestion, runny nose and sneezing of a cold. This medicine will not treat an infection.
Take this medicine by mouth. Follow the directions on the package label. Shake well before using. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
chest pain, tightness
dizziness, nervousness, or sleeplessness
fast, irregular heartbeat
trouble passing urine or change in the amount of urine
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dry eyes, mouth
loss of appetite
Do not take this medicine with any of the following medications:
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
stimulant medicines like dextroamphetamine and others
This medicine may also interact with the following medications:
medicines for anxiety or sleep
medicines for blood pressure like atenolol, clonidine, doxazosin, methyldopa, metoprolol
medicines for chest pain like isosorbide dinitrate, nitroglycerin
medicines for enlarged prostate like tamsulosin
medicines for sleep during surgery
other medicines for cold, cough or allergy
other medicines with acetaminophen
St. John's Wort
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
cough that does not go away
cough with a lot of phlegm
high blood pressure
if you often drink alcohol
taken a MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
trouble passing urine
an unusual or allergic reaction to acetaminophen, chlorpheniramine, dextromethorphan, phenylephrine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Let your doctor know if you have pain, nasal congestion, or cough that gets worse or lasts for more than 7 days. Call your doctor if you have a fever that gets worse or lasts for more than 3 days. If you have a cough that lasts more than 2 days, if your cough comes back, or if it occurs with a fever, rash, headache, nausea, or vomiting see your doctor.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.
If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.
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