Ibandronate Sodium Solution for injection

What is this medicine?

IBANDRONATE (i BAN droh nate) slows calcium loss from bones. It is used to treat osteoporosis in women past the age of menopause.

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions such as skin rash or itching, hives, swelling of the face, lips, throat, or tongue

• changes in vision

• chest pain

• fever, flu-like symptoms

• heartburn or stomach pain

• jaw pain, especially after dental work

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• bone, muscle or joint pain

• diarrhea or constipation

• eye pain or itching

• headache

• irritation at site where injected

• nausea

What may interact with this medicine?

• teriparatide

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• dental disease

• kidney disease

• low levels of calcium in the blood

• low levels of vitamin D in the blood

• an unusual or allergic reaction to ibandronate, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular check ups. It may be some time before you see the benefit from this medicine. Do not stop taking your medicine except on your doctor's advice. Your doctor or health care professional may order blood tests and other tests to see how you are doing.

You should make sure you get enough calcium and vitamin D while you are taking this medicine, unless your doctor tells you not to. Discuss the foods you eat and the vitamins you take with your health care professional.

Some people who take this medicine have severe bone, joint, and/or muscle pain. This medicine may also increase your risk for a broken thigh bone. Tell your doctor right away if you have pain in your upper leg or groin. Tell your doctor if you have any pain that does not go away or that gets worse.