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NANOPARTICLE ALBUMIN-BOUND PACLITAXEL (Na no PAHR ti kuhl al BYOO muhn-bound PAK li TAX el) is a chemotherapy drug. It targets fast dividing cells, like cancer cells, and causes these cells to die. This medicine is used to treat advanced breast cancer and advanced lung cancer.
This drug is given as an infusion into a vein. It is administered in a hospital or clinic by a specially trained health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
low blood counts - This drug may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.
signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, nosebleeds
signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness
changes in vision
high or low blood pressure
nausea and vomiting
pain, swelling, redness or irritation at the injection site
pain, tingling, numbness in the hands or feet
slow or irregular heartbeat
swelling of the ankle, feet, hands
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
changes in the color of fingernails
loss of appetite
medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim
other chemotherapy drugs like cisplatin, doxorubicin, epirubicin, etoposide, teniposide, vincristine
Talk to your doctor or health care professional before taking any of these medicines:
It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
low blood counts, like low platelets, red blood cells, or white blood cells
recent or ongoing radiation therapy
an unusual or allergic reaction to paclitaxel, albumin, other chemotherapy, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored carefully while you are receiving this medicine. You will need important blood work done while you are taking this medicine.
This medicine can cause serious allergic reactions. If you experience allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, tell your doctor or health care professional right away.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Men are advised not to father a child while receiving this medicine.
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