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ERLOTINIB (er LOE ti nib) is a chemotherapy drug. It targets a specific protein within cancer cells and stops the cancer cells from growing. This medicine is used to treat cancers including non-small cell lung cancer and pancreatic cancer.
Take erlotinib tablets by mouth. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after food. Do not take with food. Taking this drug with food may increase your chance of developing side effects. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
problems related to breathing including shortness of breath or cough
severe or persistent diarrhea, nausea, vomiting, or loss of appetite
unusual bleeding or bruising
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
loss of appetite
weak or tired
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain medicines for blood pressure
medicines for depression
medicines for fungal infections like fluconazole, itraconazole, ketoconazole, or voriconazole
non-steroidal anti-inflammatory drugs (NSAIDs such as ibuprofen or naproxen)
St. John's wort
Take your missed dose as soon as you remember. If it is almost time for your next dose, take only that one, and skip your missed dose. Do not take extra or double doses.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
previous or ongoing radiation therapy
an unusual or allergic reaction to erlotinib, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor for regular check ups. Report any side effects. Continue your course of treatment unless your doctor tells you to stop. You will need blood work done while you are taking this medicine.
If you experience any of the following, contact your health care provider: eye irritation; severe or continuing diarrhea, nausea, decreased appetite, or vomiting; or if your breathing gets worse or you develop shortness of breath or cough.
If you smoke cigarettes, you should stop smoking. The effectiveness of this drug is reduced by cigarette smoking. If you stop smoking during treatment, be sure to inform your doctor of this change.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
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