Abciximab (Murine) Solution for injection

What is this medicine?

ABCIXIMAB (ab SIX i mab) prevents blood clots during episodes of chest pain or a heart attack. It may be used during heart surgery.

How should I use this medicine?

The medicine is for injection or infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

• breathing problems

• chest pain

• unusual bleeding or bruising

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• back pain

• dizziness

• headache

• nausea

• stomach pain

What may interact with this medicine?

• aspirin and aspirin-like drugs

• clopidogrel

• dipyridamole

• herbal products containing feverfew, garlic, ginger, ginkgo, or horse chestnut

• medicines that break up blood clots like alteplase, reteplase, streptokinase, and urokinase

• medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, tinzaparin, argatroban, bivalirudin, and lepirudin

• NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen

• ticlopidine

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• bleeding problems or blood disorders

• brain tumor or aneurysm

• high blood pressure

• previous stroke

• recent injury or surgery

• took a drug to prevent blood clots like warfarin in the past week

• vasculitis

• an unusual or allergic reaction to abciximab, mouse or human proteins, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.