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Sargramostim, GM-CSF injection

What is this medicine?

SARGRAMOSTIM, GM-CSF (sar GRAM oh stim) is a granulocyte-macrophage colony-stimulating factor that stimulates the growth of certain blood cells including neutrophils, a type of white blood cell (WBC) important in the body's fight against infection. It is used to help increase WBC production after bone marrow transplantation (BMT), after BMT failure or engraftment delay, before and after stem-cell transplant, and after induction chemotherapy in older patients with acute myelogenous leukemia.

How should I use this medicine?

This medicine is for injection under the skin or into a vein. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Refer to the patient Instructions for Use for detailed instructions. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in newborns.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • chest pain

  • fast, irregular heartbeat

  • feeling faint or lightheaded, falls

  • fever (over 100.5 degrees F or 38 degrees C)

  • signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine

  • sudden weight gain

  • swelling of hands or feet

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • bone pain

  • diarrhea

  • flu-like symptoms

  • muscle aches

  • pain, redness, or swelling at site where injected

  • stomach upset

  • tiredness

What may interact with this medicine?

Do not take this medicine with:

  • medicines for cancer chemotherapy

This medicine may also interact with:

  • medicines that may cause a release of neutrophils, such as lithium or steroid medications like prednisone or cortisone

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you miss a dose.

Where should I keep my medicine?

Keep out of the reach of children.

Store in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Throw away any unused medicine after 20 days.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • fluid in the lungs

  • heart disease

  • irregular heartbeat

  • kidney disease

  • liver disease

  • lung or breathing disease, like asthma

  • ongoing radiation therapy

  • an unusual or allergic reaction to sargramostim, yeast products, benzyl alcohol, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

You may need blood work done while you are taking this medicine.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2016 Gold Standard