Need something? Call us: 1.800.4BAYLOR(1.800.422.9567)
Text Size:

Codeine Sulfate Oral tablet

What is this medicine?

CODEINE (KOE deen) is a pain reliever. It is used to treat mild to moderate pain.

How should I use this medicine?

Take this medicine by mouth with a glass of water. If the medicine upsets your stomach, take it with food or milk. Follow the directions on the prescription label. Do not take more than you are told to take.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • cold, clammy skin

  • confusion

  • fast or slow heartbeat

  • feeling faint or lightheaded, falls

  • seizures

  • trouble passing urine or change in the amount of urine

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation

  • drowsiness

  • dry mouth

  • nausea, vomiting

  • pinpoint pupils

  • sweating

What may interact with this medicine?

  • alcohol

  • antihistamines for allergy, cough and cold

  • antiviral medicines used for HIV or AIDS

  • atropine

  • certain antibiotics like erythromycin and clarithromycin

  • certain medicines for bladder problems like oxybutynin, tolterodine

  • certain medicines for depression, anxiety, or psychotic disturbances

  • certain medicines for fungal infections like ketoconazole and itraconazole

  • certain medicines for irregular heart beat like amiodarone, propafenone, quinidine

  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl

  • certain medicines for seizures like carbamazepine, phenobarbital, phenytoin

  • certain medicines for sleep

  • certain medicines for stomach problems like dicyclomine, hyoscyamine

  • certain medicines for travel sickness like scopolamine

  • certain medicines used for nausea like dronabinol, droperidol, nabilone

  • ipratropium

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • medicines for anesthesia

  • muscle relaxants

  • naltrexone

  • narcotic medicines (opiates) for pain

  • phenobarbital

  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

  • rifampin

  • tramadol

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and is against the law.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Do not use the medicine after the expiration date.

Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • brain tumor

  • drug abuse or addiction

  • head injury

  • heart disease

  • frequently drink alcohol containing drinks

  • kidney disease or problems going to the bathroom

  • liver disease

  • lung disease, asthma, or breathing problems

  • an unusual or allergic reaction to codeine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take this medicine for a long time.

Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

You may get drowsy or dizzy when you first start taking the medicine or change doses. Do not drive, use machinery, or do anything that may be dangerous until you know how the medicine affects you. Stand or sit up slowly. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

There are different types of narcotic medicines (opiates) for pain. If you take more than one type at the same time, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing.

This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Last Review Date: 8/24/2012
© 2000-2014 Krames StayWell, 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.