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L-ASPARAGINASE (L- a SPARE a gi nase) is used to treat acute lymphocytic leukemia (ALL). It is used in combination with other chemotherapy agents.
This drug is for infusion or slow injection into a vein. It is sometimes injected into a muscle. It will be given in a hospital or clinic by a trained health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
feeling faint or lightheaded
confusion, agitation, or hallucinations
fever or chills, cough or sore throat
increased amount of urine passed
severe abdominal pain
severe and sudden headache
severe nausea or vomiting
shortness of breath, chest pain, or swelling in a leg
swelling of any other parts of the body
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
loss of appetite
Talk to your doctor or health care professional before taking any of these medicines:
This does not apply. Contact your doctor or clinic if you cannot keep your appointment. It is very important to receive all your treatment as directed to achieve the best results.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
diabetes or other problems with blood sugar
history of pancreatitis
take medicines that treat or prevent blood clots
an unusual or allergic reaction to L-asparaginase, e-coli proteins, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat. Do not treat yourself.
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
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