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Tolmetin Sodium Oral capsule

What is this medicine?

TOLMETIN (TOLE met in) is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. This medicine may be used for osteoarthritis, rheumatoid arthritis, or juvenile rheumatoid arthritis.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Long-term, continuous use may increase the risk of heart attack or stroke.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • black or bloody stools

  • blood in the urine or vomit

  • blurred vision

  • breathing problems

  • chest pain

  • nausea or vomiting

  • skin rash, skin redness, blistering or peeling skin, hives, or itching

  • slurred speech or weakness on one side of the body

  • swelling of eyelids, throat, lips

  • unexplained weight gain or swelling

  • unusually weak or tired

  • yellowing of eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation or diarrhea

  • dizziness

  • gas or heartburn

  • headache

  • minor upset stomach

  • nausea, vomiting

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • cidofovir

  • methotrexate

This medicine may also interact with the following medications:

  • alcohol

  • aspirin and aspirin-like drugs

  • diuretics

  • lithium

  • medicines for high blood pressure

  • other NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen

  • pemetrexed

  • sodium bicarbonate-containing antacid

  • steroid medicines like prednisone or cortisone

  • warfarin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • asthma

  • coronary artery bypass graft (CABG) surgery within the past 2 weeks

  • drink more than 3 alcohol-containing drinks a day

  • heart disease or circulation problems like heart failure or leg edema (fluid retention)

  • high blood pressure

  • kidney disease

  • liver disease

  • stomach bleeding or ulcers

  • an unusual or allergic reaction to tolmetin, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your pain does not get better. Talk to your doctor before taking another medicine for pain. Do not treat yourself.

This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.

Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.

This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding can happen without warning symptoms and can cause death.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Last Review Date: 9/2/2009
© 2000-2014 Krames StayWell, 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.