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IBUPROFEN; PSEUDOEPHEDRINE (eye BYOO proe fen; soo doe e FED rin) is a combination of a non-steroidal anti-inflammatory drug (NSAID) and a decongestant. It is used to treat the aches and pains, congestion, and fever of the common cold, flu, or sinus problems.
Take this medicine by mouth. Follow the directions on the package label. Shake well before using. Use a specially marked spoon or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take it with or without food. If it upsets your stomach, take it with food. Try to not lie down for at least 10 minutes after you take the medicine. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
fast, irregular heartbeat
feeling faint or lightheaded, falls
high blood pressure
pain, tingling, numbness in the hands or feet
severe stomach pain
signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose
signs and symptoms of a blood clot such as changes in vision; chest pain; severe, sudden headache; trouble speaking; sudden numbness or weakness of the face, arm, or leg
trouble passing urine or change in the amount of urine
unexplained weight gain or swelling
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation or diarrhea
loss of appetite
Do not take this medicine with any of the following medications:
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
stimulant medicines for attention disorders, weight loss, or to stay awake
This medicine may also interact with the following medications:
aspirin and aspirin-like medicines
medicines for bladder problems
medicines for blood pressure, heart disease, irregular heart beat
medicines for chest pain like digoxin, nifedipine, verapamil
medicines for depression, anxiety, or psychotic disturbances
medicine for prostate
medicines for sleep during surgery
medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
other drugs for congestion, fever, inflammation, or pain
steroid medicines like prednisone or cortisone
St. John's Wort
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
This medicine may cause accidental overdose and death if taken by other adults, children, or pets. Mix any unused medicine with a substance like cat littler or coffee grounds. Then throw the medicine away in a sealed container like a sealed bag or a coffee can with a lid. Do not use the medicine after the expiration date.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).
They need to know if you have any of the following conditions:
heart disease or surgery
not drinking fluids
severe vomiting or diarrhea
stomach ulcer or other problems
taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
an unusual or allergic reaction to ibuprofen, pseudoephedrine, other fever reducers or pain relievers, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. See your doctor if fever, pain, or nasal congestion gets worse or lasts more than 3 days.
If this medicine makes it hard for you to sleep, try taking the dose earlier in the day. If you still have trouble sleeping stop taking this medicine and see your doctor.
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