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CHLORPHENIRAMINE; GUAIFENESIN; HYDROCODONE; PSEUDOEPHEDRINE (klor fen IR a meen; gwye FEN e sin; hye droe KOE done; soo doe e FED rin) is a combination of an antihistamine, an expectorant, a cough suppressant, and a decongestant. It is used to treat the cough and congestion of colds and other respiratory infections. This medicine will not treat an infection.
Take this medicine by mouth. Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take this medicine with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply. This medicine is not approved for use in children less than 6 years old.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
fast, irregular heartbeat
fear, anxiety, or restless
feeling faint or lightheaded, falls
high or low blood pressure
trouble passing urine or change in the amount of urine
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dry mouth, nose, or throat
increased sensitivity to sunlight
loss of appetite
Do not take this medicine with any of the following medications:
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
stimulant medicines for attention disorders, weight loss, or to stay awake
This medicine may also interact with the following medications:
antihistamines for allergy, cough, and cold
barbiturates like phenobarbital
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
medicines for blood pressure
medicines for depression, anxiety, or psychotic disturbances
medicines for sleep
narcotic medicines (opiates) for pain
phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Keep container tightly closed.
Throw away any unused medicine after the expiration date. Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages.
They need to know if you have any of these conditions:
drug abuse or addiction
high blood pressure
if you have taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
lung or breathing disease, like asthma
recent head injury
trouble passing urine
an unusual or allergic reaction to chlorpheniramine, codeine, guaifenesin, hydrocodone, pseudoephedrine, other medicines, foods, dyes or preservatives
pregnant or trying to get pregnant
Tell your doctor or health care professional if your symptoms do not start to get better in 5 days, if they get worse, or if you have a high fever.
Use exactly as directed by your doctor or health care professional. Do not take more than the recommended dose. You may develop tolerance to this medicine if you take it for a long time. Tolerance means that you will get less cough relief with time. Tell your doctor or health care professional if your symptoms do not improve or if they get worse.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a nonmedical reason. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
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