Toremifene Citrate Oral tablet

What is this medicine?

TOREMIFENE (tore EM i feen) blocks the effects of estrogen. It is used to treat some types of breast cancer.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• bone pain

• breathing problems

• changes in vision

• chest pain

• depression

• pain, redness, swelling in a leg

• swelling of hands, feet

• unusual bruising, bleeding

• vaginal bleeding or discharge

• yellowing of eyes, skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• dizziness

• hot flashes

• loss of appetite

• nausea, vomiting

• sweating

• unusually weak or tired

What may interact with this medicine?

• carbamazepine

• certain antibiotics, like erythromycin

• certain diuretics, like hydrochlorothiazide

• female hormones, like estrogens and birth control pills

• medicines for fungal infection like ketoconazole

• phenobarbital

• phenytoin

• warfarin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from heat and light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• blood clots

• high calcium levels

• an unusual or allergic reaction to toremifene, other medicines, foods, dyes, or preservatives

• pregnant or trying to get pregnant

• breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. You will need regular pelvic exams, breast exams, and mammograms.

If you have bone tumors, this medicine may cause bone pain and/or high blood calcium. Talk to your doctor about what symptoms are possible and what to do if you have these symptoms.