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Prednisolone Oral syrup

What is this medicine?

PREDNISOLONE (pred NISS oh lone) is a corticosteroid. It is used to treat inflammation of the skin, joints, lungs, and other organs. Common conditions treated include asthma, allergies, and arthritis. It is also used for other conditions, such as blood disorders and diseases of the adrenal glands.

How should I use this medicine?

Take this medicine by mouth. Use a specially marked spoon or dropper to measure your dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take with food or milk to avoid stomach upset. If you are taking this medicine once a day, take it in the morning. Do not take it more often than directed. Do not suddenly stop taking your medicine because you may develop a severe reaction. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose may be slowly lowered over time to avoid any side effects.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • changes in emotions or moods

  • changes in vision

  • eye pain

  • signs and symptoms of high blood sugar such as dizziness; dry mouth; dry skin; fruity breath; nausea; stomach pain; increased hunger or thirst; increased urination

  • signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine

  • slow growth in children (if used for longer periods of time)

  • swelling of ankles, feet

  • trouble sleeping

  • unusually weak or tired

  • weak bones (if used for longer periods of time)

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • increased hunger

  • nausea

  • skin problems, acne, thin and shiny skin

  • upset stomach

  • weight gain

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • metyrapone

  • mifepristone

This medicine may also interact with the following medications:

  • aminoglutethimide

  • amphotericin B

  • aspirin and aspirin-like medicines

  • barbiturates

  • certain medicines for diabetes, like glipizide or glyburide

  • cholestyramine

  • cholinesterase inhibitors

  • cyclosporine

  • digoxin

  • diuretics

  • ephedrine

  • female hormones, like estrogens and birth control pills

  • isoniazid

  • ketoconazole

  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen

  • phenytoin

  • rifampin

  • toxoids

  • vaccines

  • warfarin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

You will be instructed on how to store this medicine. See product for storage instructions. Each product may have different instructions. Most solutions or syrups are stored between 4 and 25 degrees C (39 and 77 degrees F). Keep tightly closed. Many products may be refrigerated. Do not freeze. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • Cushing's syndrome

  • diabetes

  • glaucoma

  • heart problems or disease

  • high blood pressure

  • infection such as herpes, measles, tuberculosis, or chickenpox

  • kidney disease

  • liver disease

  • mental problems

  • myasthenia gravis

  • osteoporosis

  • seizures

  • stomach ulcer or intestine disease including colitis and diverticulitis

  • thyroid problem

  • an unusual or allergic reaction to lactose, prednisolone, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. If you are taking this medicine over a prolonged period, carry an identification card with your name and address, the type and dose of your medicine, and your doctor's name and address.

This medicine may increase your risk of getting an infection. Tell your doctor or health care professional if you are around anyone with measles or chickenpox, or if you develop sores or blisters that do not heal properly.

If you are going to have surgery, tell your doctor or health care professional that you have taken this medicine within the last twelve months.

Ask your doctor or health care professional about your diet. You may need to lower the amount of salt you eat.

This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Last Review Date: 7/21/2015
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