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Progesterone Oil for injection

What is this medicine?

PROGESTERONE (proe JES ter one) is a female hormone. It is used to treat missed menstrual periods or abnormal uterine bleeding caused by a hormone imbalance.

How should I use this medicine?

This medicine is for injection into a muscle. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breast tissue changes or discharge

  • breathing problems

  • changes in vaginal bleeding during your period or between your periods

  • changes in vision

  • depression

  • numbness or pain in the arm or leg

  • pain at site where injected

  • pain, swelling, warmth in the leg

  • problems with balance, talking, walking

  • sudden severe headache

  • unusually weak or tired

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in emotions or moods

  • fluid retention and swelling

  • hair loss

  • increased in appetite

  • nausea

  • trouble sleeping

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • bosentan

This medicine may also interact with the following medications:

  • barbiturate medicines for sleep or seizures

  • bexarotene

  • carbamazepine

  • ethotoin

  • ketoconazole

  • phenytoin

  • rifampin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • blood vessel disease, blood clotting disorder, or suffered a stroke

  • breast, cervical or vaginal cancer

  • diabetes

  • heart disease

  • liver disease

  • recent abortion, miscarriage

  • vaginal bleeding

  • an unusual or allergic reaction to progesterone, other hormones, medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Last Review Date: 8/13/2009
© 2000-2014 Krames StayWell, 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.