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METOCLOPRAMIDE (met oh kloe PRA mide) is used to treat people with slow emptying of the stomach and intestinal tract. It may be used to prevent nausea and vomiting caused by cancer treatment or surgery. This medicine may also be used before certain stomach exams or procedures.
This medicine is for injection into a muscle or for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
abnormal production of milk in females
breast enlargement in both males and females
change in the way you walk
difficulty moving, speaking or swallowing
drooling, lip smacking, or rapid movements of the tongue
excessive sweating
fever
involuntary or uncontrollable movements of the eyes, head, arms and legs
irregular heartbeat or palpitations
muscle twitches and spasms
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
depressed mood
diarrhea
difficulty sleeping
headache
menstrual changes
restless or nervous
acetaminophen
cyclosporine
digoxin
medicines for blood pressure
medicines for depression, especially an Monoamine Oxidase Inhibitor (MAOI)
medicines for diabetes, including insulin
medicines for hay fever and other allergies
medicines for Parkinson's disease, like levodopa
medicines for sleep or for pain
tetracycline
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
breast cancer
depression
diabetes
heart failure
high blood pressure
kidney disease
liver disease
Parkinson's disease or a movement disorder
pheochromocytoma
seizures
stomach obstruction, bleeding, or perforation
an unusual or allergic reaction to metoclopramide, procainamide, sulfites, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
It may take a few weeks for your stomach condition to get better. However, do not take this medicine for longer than 12 weeks. The longer you take this medicine, and the more you take it, the greater your chances are of developing serious side effects. If you are an elderly patient, a female patient, or you have diabetes, you may be at an increased risk for side effects from this medicine. Contact your doctor immediately if you start having movements you cannot control such as lip smacking, rapid movements of the tongue, involuntary or uncontrollable movements of the eyes, head, arms and legs, or muscle twitches and spasms.
Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for any sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your doctor.
Do not treat yourself for high fever. Ask your doctor or health care professional for advice.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.
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