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NESIRITIDE, BNP () is a vasodilator. This medicine increases the blood and oxygen supply to your heart by relaxing blood vessels. It is used to treat congestive heart failure in patients who experience shortness of breath when at rest or during small amounts of activity.
This medicine is for infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
irregular, slow or fast heartbeat, palpitations
low blood pressure
numbness, tingling, cramps, pain or weakness in the hands, legs, or feet
trouble passing urine or change in the amount of urine
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
redness or swelling at site where injected
Do not take this medicine with any of the following medications:
sildenafil - do not take within 24 hours of this medication to avoid side effects such as low blood pressure.
This medicine may also interact with the following medications:
medicines for high blood pressure
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
low blood pressure or low blood volume
an unusual or allergic reaction to nesiritide, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
You will be closely monitored by a health care professional while you receive this medicine. Your blood pressure, heart function, and breathing will be monitored for signs of improvement in the heart failure.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more dizzy, increase flushing and rapid heartbeats. Avoid alcoholic drinks.
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